Multi-modal measurement of cortical thickness in brain MRI for Focal Cortical Dysplasia detection
Citation:
A. Kumcu, L. Platiša, I. Despotovic, E. Vansteenkiste, A. Pižurica, K. Deblaere, W. Philips, "Multi-modal measurement of cortical thickness in brain MRI for Focal Cortical Dysplasia detection", in ISMRM Benelux Chapter, 4th Annual meeting, 2012.
Bibtex Entry:
@InProceedings{Kumcu2012ISMRM,
  author    = {Kumcu, Asli and Platiša, Ljiljana and Despotovic, Ivana and Vansteenkiste, Ewout and Pižurica, Aleksandra and Deblaere, Karel and Philips, Wilfried},
  title     = {Multi-modal measurement of cortical thickness in brain MRI for Focal Cortical Dysplasia detection},
  booktitle = {ISMRM Benelux Chapter, 4th Annual meeting},
  year      = {2012},
  address   = {Leuven, Belgium},
  month     = {January},
  abstract  = {In this work we aim to improve the detection of Focal Cortical Dysplasia on MRI images using a multimodal approach. We propose to estimate the thickness of the cortex jointly using partial volume maps of T1-weighted MPRAGE and T2- weighted FLAIR images by fitting spheres into the gray matter of the brain such that the amount of probability-weighted gray matter contained in each sphere is maximized. Results on nine patients show that the FCD lesions for all patients could be detected using the multimodal approach compared to T1 alone (FCD detected in only 7 patients) and Freesurfer (4 patients).},
}
Abstract:
In this work we aim to improve the detection of Focal Cortical Dysplasia on MRI images using a multimodal approach. We propose to estimate the thickness of the cortex jointly using partial volume maps of T1-weighted MPRAGE and T2- weighted FLAIR images by fitting spheres into the gray matter of the brain such that the amount of probability-weighted gray matter contained in each sphere is maximized. Results on nine patients show that the FCD lesions for all patients could be detected using the multimodal approach compared to T1 alone (FCD detected in only 7 patients) and Freesurfer (4 patients).
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